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List of Antidepressants and Anti-Anxiety Medications
Selective serotonin reuptake inhibitors (SSRIs)
Serotonin and Norepinephrine reuptake inhibitors (SNRIs)
| Generic name |
Brand names |
| Duloxetine |
Cymbalta |
| Desvenlafaxine |
Pristiq |
| Milnacipran |
Savella |
| Venlafaxine |
Effexor XR |
Tricyclic antidepressants
| Generic name |
Brand names |
| Amitriptyline |
Elavil |
| Amoxapine |
Asendin |
| Clomipramine |
Anafranil |
| Desipramine |
Norpramin |
| Doxepin |
Sinequan |
| Imipramine |
Tofranil |
| Nortriptyline |
Pamelor |
| Protriptyline |
Vivactil |
| Trimipramine |
Surmontil |
Norepinephrine and Dopamine Reuptake Inhibitors (NDRIs)
Serotonin Antagonist /Reuptake Inhibitors (SARI)
| Generic name |
Brand names |
| Trazodone |
Oleptro |
| Etoperidone |
Axiomin, Centren, Depracer, Etonin, Etoran |
| Mepiprazole |
Psigodal |
| Nefazodone |
Serzone |
Noradrenergic and Specific Serotonergic Antidepressants (NaSSA)
| Generic name |
Brand names |
| Mirtazapine |
Remeron |
| Mianserin |
Tolvon |
| Setiptiline (licenced in Japan) |
Tecipul |
Noradrenaline reuptake inhibitors (NRIs)
| Generic name |
Brand names |
| Reboxetine |
Edronax |
| Atomoxetine |
Strattera |
| Viloxazine |
Vivalan |
Melatonin receptor agonists
| Generic name |
Brand names |
| Agomelatine |
Valdoxan |
Monoamine Oxidase Inhibitors (MAOIs)
| Generic name |
Brand names |
| Isocarboxazid |
Marplan |
| Phenelzine |
Nardil |
| Selegiline |
Emsam |
| Tranylcypromine |
Parnate |
Anti-Anxiety Medications (Anxiolytics)
| Generic name |
Brand names |
| Azapirones |
| Buspirone |
BuSpar |
| Gepirone |
Gepirone ER |
| Tandospirone |
Sediel |
| Benzodiazepines |
| Alprazolam |
Xanax |
| Chlordiazepoxide |
Librium |
| Clonazepam |
Klonopin |
| Clorazepate |
Tranxene |
| Diazepam |
Valium |
| Lorazepam |
Ativan |
| Oxazepam |
Alepam, Medopam, Murelax, Noripam, Opamox, Purata, Serax |
| Temazepam |
Restoril |
| Tofisopam (licenced in Japan, Europe) |
Emandaxin, Grandaxin |
| Antihistamines |
| Hydroxyzine |
Atarax, Tranquizine; Paxistil, Vistaril |
Over-the-counter anti-anxiety medicines
- OTC antihistamines Chlorpheniramine (Chlor-Trimeton) and diphenhydramine (Benadryl) have hypnotic, sedative, and mild
anxiolytic properties.
- Picamilon, a nootropic dietary supplement, combines gamma aminobutyric acid (GABA) and nicotinic acid (niacin, Vitamin B3). In animals studies Picamilon has been shown to improve cerebral circulation, and also work as tranquilizer with a stimulating component.
- Melatonin has anxiolytic properties, likely mediated by the benzodiazepine/GABAergic system.
- Herbal preparations: valerian, kava, chamomile.
References
- 1. Matheson GK, Pfeifer DM, Weiberg MB, Michel C. The effects of azapirones on serotonin1A neurons of the
dorsal raphe. Gen Pharmacol. 1994 Jul;25(4):675-83.
- 2. Charlton BG. Safe interventions for panic, phobia and other anxiety-disorders might include over-the-counter (OTC) 'SSRI' antihistamines such as diphenhydramine and chlorpheniramine. Acta Psychiatr Scand. 2005 Oct;112(4):323
Author: OriginalDrugs Team
Last reviewed: October 27, 2012
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Interesting Facts
- Anxiolytics are also known as minor tranquilizers.
- Beta-receptor blockers such as propranolol and atenolol, although not anxiolytics, can be used to relive the physiological r symptoms of anxiety.
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